Basic Information
VIS ID
TVIS10015988
Fusion event
HBV-chr21:q22.3 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1332
Orient
+
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
44256121/42836011 (Hg38)
End
44256121/42836011 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7c/Upstream/1089170; hsa-mir-5692b/Downstream/114917;
Nearest TSS
ENST00000624081/Upstream/53782; ENST00000460740/Downstream/466;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/149575, chr21-CpG: 27/Downstream/1845
Nearby gene
WDR4
Upstream sequence
ccatgtgaaaaacagtcaccatctacagcaggggtgtccaagcttttggcttccctgggccacactgaacaactgtattgcaccacacataaaatacact
Downstream sequence
aacattaatgatgactgatgagttaaaaaaaaaaaaatcgcaaaaaaatctcataatgtcttacgaaagtttacaaatttgtgttgggccgcattcaaag
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate