Basic Information
VIS ID
TVIS10015995
Fusion event
HBV-LOC105377858 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1819
Orient
+
Host Sequence
Chromosome
chr6
Cytoband
q13
Reference genome
GRCh37/hg19
Start
75429045/74719329 (Hg38)
End
75429045/74719329 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6D
Target gene
LOC105377858
Nearest miRNA
hsa-mir-10398/Upstream/1751576; hsa-mir-10524/Downstream/709078;
Nearest TSS
ENST00000381078/Upstream/73689; ENST00000607221/Downstream/14950;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1022918, chr6-CpG: 28/Downstream/365835
Upstream sequence
TGCAGACCAGCTGAGGGGAGGACTCCTGGGTGGACAGCCTTTGACGTCCACCCCACGCTGATGCAGAAGCTCCCAGAACACTCAGGAAACTTCTCCGGAC
Downstream sequence
tactttgtttacctttatgctccgttgaaatatttatcaatgtatgctgttcttcttcatcttctgtaaacttttctgattcaaagtctactatgtctga
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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