ARHGAP6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015997
Fusion event
HBV-ARHGAP6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1845
Orient
-
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
11223526/11205406 (Hg38)
End
11223526/11205406 (Hg38)
Orient
-
Location type
Intron
Target gene
ARHGAP6
miRNAs that regulate target gene
hsa-mir-4446-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-5088-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p
Nearest miRNA
hsa-mir-3690-1/Upstream/3078345; hsa-let-7f-2/Downstream/113208;
Nearest TSS
ENST00000429181/Upstream/23332; ENST00000348912/Downstream/60569;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/65962, chrX-CpG: 62/Downstream/222001
Upstream sequence
CCTAATGTCAAAACTTTACTGGTTTGAGAAGAATAATCAAAAAGGACTTATACCAATAGGACTTACTATTGTTTTTTAAGGATCTCCTCTCACAGTGGTA
Downstream sequence
gagggggcacaaagttgcccccagttgagaacaactgACCTGCAAAAATAAAACCTATATTCTCTCTTGGCTTATGATATACCTCAATATATTGTACCCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate