Basic Information
VIS ID
TVIS10015998
Fusion event
HBV-LOC102724542 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1823
Orient
+
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
81943431/81716307 (Hg38)
End
81943431/81716307 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC102724542
Nearest miRNA
hsa-mir-1285-2/Upstream/1849724; hsa-mir-10b/Downstream/4067293;
Nearest TSS
ENST00000437798/Upstream/248839; ENST00000448431/Downstream/289393;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/248750, chr2-CpG: 27/Downstream/2574283
Upstream sequence
CACTTCACAAACCTTGTTTGCTGCTGACAGAGACTACTGAATTAGAGCCATCATACAGAACACTGCCAATGATGGAGAGCTCAAAGTCAGCCCAATATAT
Downstream sequence
tgtcttaccctagtcctgggtctgTAGGAGGTATTTTTAGATGTTGATTGAGCAATTTTGTTTTTGTGTCACCTTACAATAGAATTCAGGGTGAGCTTCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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