Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016000
Fusion event
HBV-THRAP3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1842
Orient
-
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
Start
End
36757860/36292259 (Hg38)
Orient
-
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-615-3p ; hsa-mir-326 ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-3153 ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-3973 ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-6783-5p ; hsa-mir-548bb-5p ; hsa-mir-203a-3p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548p ; hsa-mir-5680 ; hsa-mir-625-3p ; hsa-mir-3936
Nearest miRNA
hsa-mir-12136/Upstream/1622565; hsa-mir-101-1/Downstream/869304;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/67773, chr1-CpG: 110/Downstream/13970
Upstream sequence
Tgggttccagagtcatactgctggtattcaaacttggcctctgccatttactgctcgtgtggcaggacaactcggcacttaacttctatgtgccttaact
Downstream sequence
ttgtcatcatttaaactgggcaaaataatagcacttgtcttaatcgggttaatgtgaggactatagtatacatgtcatatgctttgaacagtgactggaa
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.