Basic Information
VIS ID
TVIS10016003
Fusion event
HBV-chr5:p14.1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1910
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
26230235/26230126 (Hg38)
End
26230235/26230126 (Hg38)
Orient
+
Fragile sites / regions
FRA5E
Nearest miRNA
hsa-mir-10397/Upstream/9074134; hsa-mir-103a-1/Downstream/5705976;
Nearest TSS
ENST00000502646/Upstream/784201; ENST00000514255/Downstream/169693;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/320584, chr5-CpG: 28/Downstream/439313
Upstream sequence
aaccacacctccattccccacagcagctgcaggagagcctatacccaaggcgagtctgagctcacctaaccctgctcacacctcatggtctttctctacc
Downstream sequence
GTGAAAATCTTGTTGGCAGAAGAAAGTCACCCAGCCACGAGCAACACCTCTGGGATGGATAAGTCTATCCACCCTCCCTTGCTGCCGACTAATGCAGCAT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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