Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016007
Fusion event
HBV-KLKB1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1819
Orient
-
Host Sequence
Chromosome
chr4
Cytoband
q35.2
Reference genome
End
187153985/186232831 (Hg38)
Orient
+
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/1294391;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/28373, chr4-CpG: 36/Downstream/65335
Upstream sequence
gtgttttgttttgtttatatttttgtaaaaatgggcaatcagattttaagactaatggaatgcaaagagtctcaattagccaagctattctaaaaagaac
Downstream sequence
tgtgtgtgtgtatgtgtgcttgtgcttgtgtgaatatgtatTATTAACTGGAAATTTGTAAAAGTATTGGAAAAATAGTACTTACGATTTTGTGTGTGTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.