Basic Information
VIS ID
TVIS10016014
Fusion event
HBV-chr5:q31.2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1814
Orient
+
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
137882222/138546533 (Hg38)
End
137882222/138546533 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/898884; hsa-mir-103a-1/Downstream/2017138;
Nearest TSS
ENST00000502646/Upstream/3233; ENST00000521941/Downstream/11358;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2797, chr5-CpG: 67/Downstream/28711
Nearby gene
HSPA9
Upstream sequence
CACGTTCTATGACTAACTACTTCTAAAAAACAAAATTTGGACCCAGTTGTAAAAGAAATCTGAGAGCAAATACATGTTTCTGTGGATCTTTAATGGGAGG
Downstream sequence
tctcagaacttcctcctcagctcaaacattatgtaaCAAAGTTAAATATTGGGATATAGGTGATGTTCCTACCTAATTAGGTGGGAGTAGGCAAGTAAGt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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