LINGO2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016019
Fusion event
HBV-LINGO2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1834
Orient
-
Host Sequence
Chromosome
chr9
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
28111291/28111293 (Hg38)
End
28111291/28111293 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9C
Target gene
LINGO2
miRNAs that regulate target gene
hsa-mir-587 ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-2115-5p ; hsa-mir-1976 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-660-3p ; hsa-mir-5193
Nearest miRNA
hsa-mir-101-2/Upstream/6599108; hsa-let-7a-1/Downstream/752333;
Nearest TSS
ENST00000422679/Upstream/282017; ENST00000541043/Downstream/184038;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/537304, chr9-CpG: 74/Downstream/1100880
Nearby gene
PNOC
Upstream sequence
TATTATTTGCTTTGTCCGGCCCTACTTGGCTGAGGACTCGCAAGACATTTCCCTACACATCGTCAAATCTTCATAATCTCTAACTACTCAAAACTCTTTC
Downstream sequence
CACCCCGGCCTCATGGCCACAGGGCCCCTCCCTGGTCCTGTTCTTGCTCCAGGGCCACGGCCCACGCTGCGGTTCAGGCATGTGTGGAGCCAGGCAGGGT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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