Basic Information
VIS ID
TVIS10016020
Fusion event
HBV-CEMIP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1789
Orient
+
Host Sequence
Chromosome
chr15
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
81194935/80902594 (Hg38)
End
81194935/80902594 (Hg38)
Orient
-
Location type
Intron
Target gene
CEMIP
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-216a-5p ; hsa-mir-188-5p
Nearest miRNA
hsa-mir-10393/Upstream/60521; hsa-mir-11181/Downstream/94823;
Nearest TSS
ENST00000557528/Upstream/123223; ENST00000560027/Downstream/575;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/121715, chr15-CpG: 56/Downstream/86943
Upstream sequence
CATTATTTCCTGGAAAGGCCCTCTGAGACCTTGAGCATAAAAGAGCCTATTTCAAACCGGAGGATGCTCTCTGGTCCGTACGGTACCCACAGGGACACAG
Downstream sequence
CTGCAGCCGGGAAGACGGCTGTGGGACTGAAATATTCTTGCAGCTCTCAATCTGACTTATATTTCCTTGGCTGACGGGAGTCTGATAAACACAGTGCCTC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate