Basic Information
VIS ID
TVIS10016023
Fusion event
HBV-LOC105378641 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1701
Orient
+
Host Sequence
Chromosome
chr1
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
35134492/34668891 (Hg38)
End
35134492/34668891 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105378641
Nearest miRNA
hsa-mir-12136/Upstream/1336399; hsa-mir-101-1/Downstream/708;
Nearest TSS
ENST00000473358/Upstream/491221; ENST00000338513/Downstream/86156;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/491468, chr1-CpG: 22/Downstream/92536
Nearby gene
PARD3
Upstream sequence
TACTTTTTCTAAATGAAAGGTCTTCTCTAGACTTCACTTCCTCTAAGAAGTTAAAATTTAGCCCTCTGAGAAAAAAAACGAGAAACGTAATAGGAAGGTA
Downstream sequence
AAGCGTGGCAAATTGTTTATCGTGTCATGTAATTTACTGTGCAACTCTCCTGGCCCCTTTTCCTACCTACTCCCAACCTTTTTCATAACTTTTCAAGAGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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