Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016024
Fusion event
HBV-TYR integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1796
Orient
-
Host Sequence
Chromosome
chr11
Cytoband
q14.3
Reference genome
Start
End
88936794/89203626 (Hg38)
Orient
+
Location type
Intron
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/1027033; hsa-let-7a-2/Downstream/1352148;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/137516, chr11-CpG: 39/Downstream/287622
Upstream sequence
GAATAGAAAAAATACAGTGAAGTATAAAATCTAAAATATACTTTGCAAATAATGTTTCATAATTATTTTTAAGGATGATAAGATAAAAGAAATTACGTAA
Downstream sequence
AGCTGTCTTATAGAATAAACACCTAATCTATGGCATACAAATCAGAATGAAAGGGTTAGAATTTAGTCTTTTCCTACATAAAAATATCCTATGCCTTCCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.