Basic Information
VIS ID
TVIS10016029
Fusion event
HBV-chr3:q13.13 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1842
Orient
-
Host Sequence
Chromosome
chr3
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
109526213/109807366 (Hg38)
End
109526213/109807366 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7g/Upstream/204469; hsa-mir-12124/Downstream/2305435;
Nearest TSS
ENST00000440867/Upstream/159259; ENST00000478327/Downstream/722216;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/689124, chr3-CpG: 105/Downstream/1263936
Upstream sequence
GGCTGAACCAAATCCATCCATCCATGTCTGACCAGTTTCTCTTCTAGGTTAAGGGTTAGTTCCAGTCTTTGCCACAACTCCTCTTCCTCTTTTGTTCCAG
Downstream sequence
ttttgcttgcaaataaggaccttgcttgatGTATTGTCTATCTCTTAGGCCAAAAGAATAGAGGCCAGAGAAGAGGAGCCAGGCTGGTAGAAACATCTCG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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