Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016032
Fusion event
HBV-DNER integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1777
Orient
-
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
End
230315084/229450368 (Hg38)
Orient
-
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/1978181; hsa-mir-1244-1/Downstream/1912340;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/178933, chr2-CpG: 180/Downstream/262978
Upstream sequence
TAGAAAAAGCCTTTGAAATAACTGCAGAAAATAATGTAACAGTTTTTGTTTTACTGAATCATTTTATAATACTTAAGAATCAAAAATGAAATGACCCTTA
Downstream sequence
ACTAGAACCCAGTAGAAGAGTTAATATTAAATATAGTTCTCAGTGGAGGTTGATAGTTAAGCATTGGATTAGCAAtgtcatgggttaaattgcgtccctc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.