Basic Information
VIS ID
TVIS10016033
Fusion event
HBV-chr2:q32.2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1818
Orient
-
Host Sequence
Chromosome
chr2
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
194378211/193513486 (Hg38)
End
194378211/193513486 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10b/Upstream/4380375; hsa-mir-1244-1/Downstream/13269748;
Nearest TSS
ENST00000437798/Upstream/763519; ENST00000569293/Downstream/384881;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1317400, chr2-CpG: 150/Downstream/2143345
Upstream sequence
ccggctaatttttgtattttttgtagagacttggtctcactgtgttgcccaggctggtctcgaactcctgggctcaagcaattggcccacctcagcctcc
Downstream sequence
CTCTTAAGCTTCTAAAATTTATTGCAAAGAGTAAAATACCGAAAGAGTCAGAGATAAGTTAATCAAAAACAAGTTACTTAAAAATTAAATTTATGAAACA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate