Basic Information
VIS ID
TVIS10016034
Fusion event
HBV-LOC105372242 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1824
Orient
-
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
3072886/3072888 (Hg38)
End
3072886/3072888 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
LOC105372242
Nearest miRNA
hsa-mir-1227/Upstream/442095; hsa-let-7e/Downstream/888526;
Nearest TSS
ENST00000633603/Upstream/9781; ENST00000586763/Downstream/21522;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/10088, chr19-CpG: 26/Downstream/21255
Nearby gene
TLE5
Upstream sequence
GGTAGGTGGGGAGACTGGACAGCCATGTCAGGTTTGGGGATGACCCCACACTTGGGTGACATGCACCAAGAGCCTAGGAGAGAGGGAGCCAAGTCAGGTG
Downstream sequence
acagtgacccacatagctccaaccttacagcctagcaggggagccagacattaataaaatcactatacaaacatatgtggtTATaatccctcagcaatcc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate