VISDB Viral Integration Site DataBase

VIS ID

TVIS10016035

Fusion event

HBV-FKBP5 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

1842

Orient

+

Chromosome

chr6

Cytoband

p21.31

Reference genome

Start

End

35595968/35628191 (Hg38)

Orient

-

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-93-3p ; hsa-mir-328-3p ; hsa-mir-22-3p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-6516-5p ; hsa-mir-550b-2-5p ; hsa-mir-4443 ; hsa-mir-455-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1243 ; hsa-mir-3654 ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-302c-5p ; hsa-mir-7106-5p ; hsa-mir-6878-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-6133 ; hsa-mir-765 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-539-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-6760-5p ; hsa-mir-7977 ; hsa-mir-3166 ; hsa-mir-3664-3p ; hsa-mir-5690 ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-4666a-5p ; hsa-mir-4740-5p ; hsa-mir-4272 ; hsa-mir-6816-3p ; hsa-mir-3169 ; hsa-mir-8080 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-4485-5p ; hsa-mir-511-5p ; hsa-mir-28-5p ; hsa-mir-3139 ; hsa-mir-3190-5p ; hsa-mir-3613-3p ; hsa-mir-3675-3p ; hsa-mir-3926 ; hsa-mir-4684-5p ; hsa-mir-4786-5p ; hsa-mir-548c-3p ; hsa-mir-548s ; hsa-mir-5589-5p ; hsa-mir-6771-3p ; hsa-mir-6776-5p ; hsa-mir-6849-3p ; hsa-mir-708-5p

Nearest miRNA

hsa-mir-1236/Upstream/157612; hsa-mir-10398/Downstream/36526;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/115814, chr6-CpG: 165/Downstream/59639

Upstream sequence

TGGAGAATAACTTTGTTAATTAATACAATATTTATTGAATGAATAGGAGTAAGAAATCAGCAACAGTTGTTCTTACtttattatgtttttatctatttat

Downstream sequence

tttacatgtggatatctagcttttccaacaccatttgttgaaaagactgttctttctcccactgaatggtcttggcacccttgttgaaaaATCACTACCT