Basic Information
VIS ID
TVIS10016054
Fusion event
HBV-chr5:q31.3 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1465
Orient
-
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
141209672/141830107 (Hg38)
End
141209672/141830107 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10397/Upstream/1182181; hsa-mir-103a-1/Downstream/1849753;
Nearest TSS
ENST00000502646/Upstream/3782; ENST00000506775/Downstream/36095;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/76336, chr5-CpG: 102/Downstream/19258
Nearby gene
PCDH1
Upstream sequence
CATACTTAGCTCTTGAGCACCTTAGCGGGGGTGTCCTTCTTGGGAAAAGTTTTGGAACCCTAatttagtccaattaccataatttacacatgaaggaact
Downstream sequence
ttgcccaggctggagtgctgtggtgcagttatcggctcactgcaacctccgcctcctgggttcaagcaattcttctgccttggcctcctgagtagctggt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate