Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016056
Fusion event
HBV-ZBTB16 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1811
Orient
+
Host Sequence
Chromosome
chr11
Cytoband
q23.2
Reference genome
End
113977215/114106493 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-5580-3p ; hsa-mir-190a-3p ; hsa-mir-301b-3p ; hsa-mir-3145-3p ; hsa-mir-186-3p ; hsa-mir-5685 ; hsa-mir-4699-3p ; hsa-mir-4690-3p ; hsa-mir-3908 ; hsa-mir-330-3p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-6749-3p ; hsa-mir-452-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-4469 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-5088-3p ; hsa-mir-5193 ; hsa-mir-1470 ; hsa-mir-4667-3p ; hsa-mir-1306-5p ; hsa-mir-5011-5p ; hsa-mir-6778-3p ; hsa-mir-3162-3p ; hsa-mir-361-3p ; hsa-mir-6849-3p
Nearest miRNA
hsa-mir-10392/Upstream/656405; hsa-let-7a-2/Downstream/4537507;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/23376, chr11-CpG: 24/Downstream/92648
Nearest cancer related gene
ZBTB16(TSG, No orient, 0)
Upstream sequence
cataaattgacataaccctttgagaaagcaatttgctaacctgttttaagaaccataaaccatgtgctttgacttggtaatcatatctctgaggatttct
Downstream sequence
cctcaagaaataatcaaaaaCAAGGCCAAGGTTAGGCCCAAAGCATAAGGGAATTGGTGAAGATATGACATCAGAATATATACTCAACAACATCAGGCCT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.