Basic Information
VIS ID
TVIS10016058
Fusion event
HBV-chr2:q33.2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1760
Orient
+
Host Sequence
Chromosome
chr2
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
204436340/203571617 (Hg38)
End
204436340/203571617 (Hg38)
Orient
-
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/14438506; hsa-mir-1244-1/Downstream/3211617;
Nearest TSS
ENST00000437798/Upstream/36207; ENST00000458610/Downstream/134858;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/36171, chr2-CpG: 83/Downstream/973599
Nearby gene
RAPH1
Upstream sequence
AGTTTTCTCTCCTCAAGGTTGTAACTATGTGAAAGTCAAAACCCTGGAAAAACTGAGCCAGTAAGAGATTGAGTGCTACACAAAACTTTGCCAAAACTCT
Downstream sequence
caacagagtgagactctgtctcaaataaataagtaaaatagtaaaataaaatataataaaagattatgatgaatatagcacataaattgactttaaaaac
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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