Basic Information
VIS ID
TVIS10016063
Fusion event
HBV-chr4:q22.2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1834
Orient
-
Host Sequence
Chromosome
chr4
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
94731754/93810603 (Hg38)
End
94731754/93810603 (Hg38)
Orient
+
Fragile sites / regions
FRA4E
Nearest miRNA
hsa-mir-12113/Upstream/6510020; hsa-mir-1243/Downstream/5186784;
Nearest TSS
ENST00000502981/Upstream/41373; ENST00000306011/Downstream/18150;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1504747, chr4-CpG: 112/Downstream/17741
Nearby gene
GRID2
Upstream sequence
TAGTAGAGTCAGTTTCATTCTTATGCTAGTGCAGGGAACCTAGCTTTCAGCCTGGCCTGATTAGAAGATACCCACAGGATCAAACAAAAGCCTCACCACA
Downstream sequence
GAACATTTCAAGTTAGCTTCAATCTACAAATTGTACCTCTCTTTCAAAAGTCAGAGGCAATCAACTCTGCCACTGCCGCATCAGAATGCAGAGACTGCCC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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