TCF12 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016066
Fusion event
HBV-TCF12 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1828
Orient
-
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
57550070/57257872 (Hg38)
End
57550070/57257872 (Hg38)
Orient
+
Location type
Intron
Target gene
TCF12
miRNAs that regulate target gene
hsa-mir-204-5p ; hsa-mir-211-5p ; hsa-mir-375 ; hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-1224-3p ; hsa-mir-548v ; hsa-mir-33a-3p ; hsa-mir-139-5p ; hsa-mir-8485
Nearest miRNA
hsa-mir-10393/Upstream/1884838; hsa-mir-11181/Downstream/1913311;
Nearest TSS
ENST00000557528/Upstream/5673; ENST00000561454/Downstream/23775;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/338065, chr15-CpG: 58/Downstream/48468
Upstream sequence
AAAAAAAAAACCCAAATCTGCAAATGATTTACTTCTGTGTGTGTGTGTTTAAAAATAACGTTTATTGAAGTTATACAtttttgttctttttttttttttt
Downstream sequence
AGTTTTTAGAACTATTGAAATGTCAGCATTTGGCTTTAGTTTTGTTCCCATTTATTTAGCGTAAGGCTAAACTTTTAGAATAAACTGCTGAGAAGAAGGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate