Basic Information
VIS ID
TVIS10016067
Fusion event
HBV-chr1:q31.1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1824
Orient
-
Host Sequence
Chromosome
chr1
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
188267331/188298200 (Hg38)
End
188267331/188298200 (Hg38)
Orient
-
Fragile sites / regions
FRA1K
Nearest miRNA
hsa-mir-101-1/Upstream/7859810; hsa-mir-1182/Downstream/4418128;
Nearest TSS
ENST00000473358/Upstream/79800; ENST00000426262/Downstream/210338;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1617251, chr1-CpG: 56/Downstream/4510302
Upstream sequence
CCAGCCAGCGCTAGTGGCAGCTGGGTTCCGGGCAGGTGGAGCCGACGTGGTCTGGAGCCCGCAGCCACACTCTGGCACCTCCTCAGGCGGTTTTCAAGGG
Downstream sequence
TGGGTTCCAGCCAGGCAAGTCCTACGCACTCCTGCCTAGGTGGCATGGCCACGGGAAGGACAGCCTCAGGAGGTAGATGGACAAGGACCCTCCTTGCCTG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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