Basic Information
VIS ID
TVIS10016071
Fusion event
HBV-chr14:q31.3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1801
Orient
-
Host Sequence
Chromosome
chr14
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
88387716/87921372 (Hg38)
End
88387716/87921372 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1260a/Upstream/10655082; hsa-mir-1185-1/Downstream/6026854;
Nearest TSS
ENST00000550708/Upstream/49081; ENST00000267549/Downstream/28527;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/2387238, chr14-CpG: 87/Downstream/71180
Nearby gene
GALC
Upstream sequence
ctgagtgTttttctgttgctacgaaggaatagctgaggctgggtaatttataaagaaaagaggtttattttctcatggttctgcaggctgttcaaggagc
Downstream sequence
ATTAATGGATCTTTACACCTTTTACACTGCTAGGGAAAAAATATCATCACAGTTAGACTAATTGTAAGTTTTTTATTCAACATTCATTCAACAAATACTT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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