Basic Information
VIS ID
TVIS10016083
Fusion event
HBV-chr18:q21.31 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1818
Orient
-
Host Sequence
Chromosome
chr18
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
56099830/58432598 (Hg38)
End
56099830/58432598 (Hg38)
Orient
-
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/2953300; hsa-mir-122/Downstream/18476;
Nearest TSS
ENST00000575820/Upstream/15833; ENST00000590797/Downstream/13677;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/175762, chr18-CpG: 92/Downstream/238381
Nearby gene
NEDD4L
Nearest cancer related gene
NEDD4L(TSG, No orient)
Upstream sequence
caaactgagaggcagttactccagaggaatggcaggaacttggaggaagaacactgggagtctttagctttctagccacaggctattagtcctccccacc
Downstream sequence
gatatctcatctacacttacataattaggagtgaagttaactatgttttcatgtgtttatttttctgtaaacttcacattcatatcctttccagatttcc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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