Basic Information
VIS ID
TVIS10016086
Fusion event
HBV-chr6:q12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1826
Orient
+
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
67844513/67134620 (Hg38)
End
67844513/67134620 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/9744408; hsa-mir-10524/Downstream/4242340;
Nearest TSS
ENST00000381078/Upstream/1427395; ENST00000449928/Downstream/754719;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1039682, chr6-CpG: 37/Downstream/1500220
Upstream sequence
GTGAAATAAATGATTACTAAATTGTATACACATAAATCTTCAGTTGGCTTTTGGCACCTGAGATACACATCTGTTGCCTCCATCAATTCTACACATTCTT
Downstream sequence
ATCTGATTTTAAACTTTCCCCATTGGATTACATTGCTTTCTTTAATTCACTATTCTTCTGCACACCCAGTAAATCATCACTCTTCCTCATGATTGTGTCT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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