VISDB Viral Integration Site DataBase

VIS ID

TVIS10016088

Fusion event

HBV-MTHFD1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

1829

Orient

-

Chromosome

chr14

Cytoband

q23.3

Reference genome

Start

End

64914527/64447809 (Hg38)

Orient

+

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-324-5p ; hsa-mir-106b-5p ; hsa-mir-17-3p ; hsa-let-7a-5p ; hsa-mir-9-5p ; hsa-mir-197-3p ; hsa-mir-548ag ; hsa-mir-2681-5p ; hsa-mir-1273g-5p ; hsa-mir-203a-5p ; hsa-mir-4714-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-4999-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-6867-5p ; hsa-mir-3713 ; hsa-mir-548q ; hsa-mir-548aw ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-1273e ; hsa-mir-139-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6840-3p ; hsa-mir-4768-3p ; hsa-mir-34b-3p ; hsa-mir-1285-3p ; hsa-mir-3187-5p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-4640-5p ; hsa-mir-4726-5p ; hsa-mir-5189-5p ; hsa-mir-612 ; hsa-mir-6508-3p ; hsa-mir-6860 ; hsa-mir-1273a ; hsa-mir-1273g-3p ; hsa-mir-1292-3p ; hsa-mir-3614-5p ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4252 ; hsa-mir-4649-5p ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-616-5p ; hsa-mir-6500-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-665 ; hsa-mir-6720-5p ; hsa-mir-6729-5p ; hsa-mir-6760-3p ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-939-3p ; hsa-mir-1200 ; hsa-mir-215-3p ; hsa-mir-3140-5p ; hsa-mir-378a-5p ; hsa-mir-4452 ; hsa-mir-4680-3p ; hsa-mir-506-5p ; hsa-mir-616-3p ; hsa-mir-649

Nearest miRNA

hsa-mir-208a/Upstream/352684; hsa-mir-1185-1/Downstream/337817;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/59503, chr14-CpG: 62/Downstream/17352

Upstream sequence

CAGAAAGCAGAGCCCATCTCCCATATCCACTGGAGACTGAGAAATGAATACTGAGACTAATGGGCTCAAGGACATCTAGGGATGAAAAAGATGAAGCCAG

Downstream sequence

GAGTAGAGTTAATTTGTATTATCATAACCCTATGAATACATAAAATCTATAAACACAATTGGTAAATATAATTTGGGTAAGGGTAACTAATTCCTTTCAA