Basic Information
VIS ID
TVIS10016092
Fusion event
HBV-LOC401478 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22962577
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1774
Orient
+
Host Sequence
Chromosome
chr8
Cytoband
q24.23
Reference genome
GRCh37/hg19
Start
138952687/137940444 (Hg38)
End
138952687/137940444 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC401478
Nearest miRNA
hsa-mir-1204/Upstream/3135499; hsa-mir-10400/Downstream/2792120;
Nearest TSS
ENST00000518652/Upstream/88117; ENST00000521793/Downstream/122824;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/2482345, chr8-CpG: 119/Downstream/556108
Upstream sequence
TTCAGAGGACTAGAAGAACAAGGCATCTGACTGGAGAGTTACTGGGCCTGTGGACTCCTAAGACTGGTATAAAACCGTTTTTGCTAGAGTCGGCAAGCTT
Downstream sequence
TCGTCTCAAGGTGACAACTTTCTCTTTGATGGTGGAAGCATACTCTTCAGGCAGAAACTCATGCCTTACAAACCTTCGGTAAGGCAGAAGCCATGGCCCG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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