Basic Information
VIS ID
TVIS10016096
Fusion event
HBV-chr15 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1657
End
1723
Orient
+
Integrated sequence
ACTTCTCTCAATTTTCTAGGGGGAACACCCGTGTGTCTTGGCCAAAATTCGCAGTCCCAAATCTCCA
Host Sequence
Chromosome
chr15
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
32971199/32678998 (Hg38)
End
32971303/32679102 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1268a/Upstream/1613857; hsa-mir-10393/Downstream/1702967;
Nearest TSS
ENST00000557528/Upstream/1438; ENST00000498607/Downstream/5314;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/63249, chr15-CpG: 217/Downstream/38227
Nearby gene
LOC105370757(-5933) ; LOC105370756(+7864) ;
Upstream sequence
AGCCTGGGAGTGGCCAGTGAAGGCGGCAGCAGGACAGATAAGGTGGCTGCCGCAGCTAACAGCCATGGCCAGGTCTTGTAAAAGGTTCTGATAGGAAGCT
Downstream sequence
acccatctgtgttgatgccacttagtttccagcttttccaagaagccctcccatcccatcagccaaatggaactctccctttcccatgctcttttttttt
Target sequence
ATCTTTTTTCATAATGTGCTTTCAGCCTGTATTTCTGGATGGCAATTGCCTTCCTTTCTTGACCCAAGTCCTGCCCAAGCTCCACGCCCAGCTTCCAGAGCcct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate