Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016097
Fusion event
HBV-LUC7L integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1798
End
1820
Orient
-
Integrated sequence
CTCTGCATCCTGCTGCTATGCCT
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
Start
End
251078/201079 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-3685 ; hsa-mir-155-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4711-5p ; hsa-mir-107 ; hsa-mir-1827 ; hsa-mir-103a-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-10b-3p ; hsa-mir-4695-5p ; hsa-mir-122-5p ; hsa-mir-129-5p ; hsa-mir-3135b ; hsa-mir-3160-5p ; hsa-mir-3652 ; hsa-mir-3655 ; hsa-mir-4430 ; hsa-mir-500b-3p ; hsa-mir-504-3p ; hsa-mir-5698 ; hsa-mir-578 ; hsa-mir-6879-3p ; hsa-mir-8055
Nearest miRNA
hsa-mir-6859-4/Upstream/183896; hsa-mir-11401/Downstream/334237;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/13731, chr16-CpG: 82/Downstream/27760
Upstream sequence
AATACTACATTCTAGTTCTGTTTTCGTTTATTTTAAAACTGAATCCTTAAACTTGCAAACACGCCTACTGTAAGCATGCTTGGAATGACTTGTTTTGGTT
Downstream sequence
aattacttgaacccgggagtcagaggatgcagtgagccgagatcgcaccacagcaatccagcctgggcgacagagcgagactctgtctgagaaaaaaaaa
Target sequence
aaaaattagctgggcacggtggctggcacctgtaatcccagctactcgggaggctgagtctgag
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.