Basic Information
VIS ID
TVIS10016098
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
3106
Orient
+
Integrated sequence
AGACCACCGTGAACGCCCACTGGAACCTGCCCAAGGTCTTACAGGAGAGGACTCTTGGACTTTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAA| |AGACTGTGTGTTTGCTGAGTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTATTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCA
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
43236625/45159258 (Hg38)
End
43236625/45159258 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1180/Upstream/44825; hsa-mir-10226/Downstream/316105;
Nearest TSS
ENST00000595228/Upstream/10756; ENST00000591070/Downstream/197;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/9009, chr17-CpG: 83/Downstream/1635
Nearby gene
HEXIM1(-7157) ; HEXIM2(+1638) ;
Upstream sequence
ACTTATTTTTAAAAAGATTcacacctatagtcccagctactcgggaggccaaggcaggagaatcacttgaacctggtaggcagaggctgcagtgagccga
Downstream sequence
GTCTTTAAAAGCCTTTTCTGTTCCTATGACTATTTAAGTCCTACCAAGTTAGTTAGCTTTTTTAAACTCACATCTCTTGATCAGTGTAGAGCGAACATGT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate