Basic Information
VIS ID
TVIS10016101
Fusion event
HBV-chr19 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1685
Orient
-
Integrated sequence
CTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAAAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACAC| |CCGTGTGTCTTGGCCAAAATTCGCAGTCCCAAATCTCCAGTCACTCACCAACTTGTTGTCCTCCAATTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCG
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
21096468/20913662 (Hg38)
End
21096468/20913662 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10395/Upstream/514308; hsa-let-7e/Downstream/14209038;
Nearest TSS
ENST00000633603/Upstream/137237; ENST00000596476/Downstream/9560;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/861364, chr19-CpG: 19/Downstream/168696
Nearby gene
ZNF626(-252066) ; ZNF85(+9590) ;
Upstream sequence
caccgcgcctggccAACagcaatgatctttgagcacctatattgccagtctccacggtaagagctttcttcattttttgttttgttttgtttcaagacag
Downstream sequence
GTCACCCACTTATTTATCACAGTGGGAAAGTGATCACTGTCAGCCACATTCACCACAGTGGGATATTGTTGACTGTCAGCCCCTCACTCACCACAGTAGG
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate