TUBA8 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016102
Fusion event
HBV-TUBA8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
2684
Orient
+
Integrated sequence
ACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCGCGGAACCTTTGTGTCTCCGCTGCCGATCCATACTGCGGAACTCCTAGCAGC| |TTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGGACTGATAATTCTGTCGTGCTCTCCCGCAAGTATACGTCGTTTCCATGGCTGCTAGGCTGT
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
18597362/18114595 (Hg38)
End
18597362/18114595 (Hg38)
Orient
-
Location type
Intronic
Target gene
TUBA8
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-3198-1/Upstream/133634; hsa-let-7a-3/Downstream/1849158;
Nearest TSS
ENST00000624155/Upstream/3802; ENST00000416740/Downstream/6512;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/3164, chr22-CpG: 32/Downstream/35374
Nearby gene
PEX26(-23565) ; USP18(+35395) ;
Upstream sequence
TCAAATATGCCCTATGATCGAAGAGTTCTGAGCAGAGAGAATTCAGCAGCCCTTCAGGAGCCACATCTGTCCTTACTTTAATTACCCCTCTGTGACACTG
Downstream sequence
TGGGCCTGCTTTTCACTTGCCATCCCTGACCTAGGTCCTAAGATATATGTGATCTATTTTATCCCAGCCTGACAACTAGAGATAATTCGGTGTAATCACA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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