Basic Information
VIS ID
TVIS10016108
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
547
Orient
-
Integrated sequence
GAGTGTGGATTCGCACTCCTCCTGCATATAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCC| |TAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCACCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCA
Host Sequence
Chromosome
chr4
Cytoband
q31.22
Reference genome
GRCh37/hg19
Start
147052284/146131132 (Hg38)
End
147052284/146131132 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-12113/Upstream/2787597; hsa-mir-1305/Downstream/277451;
Nearest TSS
ENST00000502981/Upstream/9219; ENST00000510331/Downstream/44553;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/193202, chr4-CpG: 70/Downstream/44593
Nearby gene
ZNF827(-192677) ; LSM6(+44550) ;
Upstream sequence
atatttctggttgtttccattattcaaatgagtaaaccttggcacagagggatgacaaggtatcacatcttagtaagtggtgaagactgggcaaaaattg
Downstream sequence
CTCccaccccattggcaggccctgtaagttatcttccaaaaaaaacccaagtcagttttctcttatcccttctcactgctgcccccagcctcatctaagc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate