Basic Information
VIS ID
TVIS10016109
Fusion event
HBV-chr5 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1779
End
1801
Orient
-
Integrated sequence
GCGGCGTTTTATCATCTTCCTCT
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
115374568/116038871 (Hg38)
End
115374635/116038938 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10397/Upstream/5524956; hsa-mir-103a-1/Downstream/216805;
Nearest TSS
ENST00000502646/Upstream/6547; ENST00000634632/Downstream/12528;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/75431, chr5-CpG: 61/Downstream/45946
Upstream sequence
ttgtactgtgcctggtacataaaaatgcatggtaaattgttgttGTTATAACGATGGGGAATGCCAGCACTAAACAAAAGATTTAGggactaaatgagat
Downstream sequence
CCCAGACAGCCTTTCAGGGAGTCCCTGGGGCCCAGGGGTGGCGGAGGAAATGAAGCAGAATGAGGAAATGCACAGACAAACCGCCCTTGCTGTCTGGTAG
Target sequence
CAGAACCTTCCAAAATTAAGTGGCTCACCATGAGAGGCCAAACCTGTAACACTTTGTAATTACAAGC
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate