Basic Information
VIS ID
TVIS10016110
Fusion event
HBV-LOC105377706 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1905
Orient
+
Integrated sequence
TCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCATCAACCACCAGCACCGG| |ACCATGCAGAACCTGCACGACTCCTGCTCAAGGAACCTCTATGTTTCCCTCATGTTGCTGTACAAAACCTATGGACGGAAACTGCACATGTATTCCCATC
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37/hg19
Start
166295733/166868728 (Hg38)
End
166295733/166868728 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377706
Nearest miRNA
hsa-mir-10397/Upstream/6383278; hsa-mir-103a-1/Downstream/1297117;
Nearest TSS
ENST00000502646/Upstream/740230; ENST00000517586/Downstream/57642;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/3362788, chr5-CpG: 17/Downstream/109751
Nearby gene
MAT2B(-3349405) ; TENM2(+416109) ;
Upstream sequence
CTCTGTCTCTAGAGAGACAGGTAGAGATCTGAGATTTTGGACAGCCCAGTTATTATTCATGTGGCTTCAGTATATTCTCACGTCACAGGGTATGCTAATA
Downstream sequence
GACGTTCTTCTAGCTCCTATGACTACCTCCAGTTTTCTTCCAGCCACGTGGGCTGCCCCTTCTCAGGATCCCTGGCAGTCTTCTGCTATGATTCACTGGA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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