Basic Information
VIS ID
TVIS10016114
Fusion event
HBV-chr7 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1774
End
1796
Orient
-
Integrated sequence
TGTCTGCGGCGTTTTATCATCTT
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
109281775/109641718 (Hg38)
End
109281835/109641778 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10525/Upstream/7170187; hsa-mir-10399/Downstream/5011567;
Nearest TSS
ENST00000635602/Upstream/44552; ENST00000464835/Downstream/892976;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1071256, chr7-CpG: 68/Downstream/1920245
Upstream sequence
AAATGGAAACAAAACTAACAAAAAGTTGGGAATACGTGGCCAtttataaagtactttcaaataagtcatctcatttgatcttcataatgatgtaaaatat
Downstream sequence
ggtgcaggcggtctgagtccgaaaagagtgttagagaagggatatagggctggggctgttttataggatttgggtgggtagtagaaaattacagtcaaag
Target sequence
tccgtgtgaagagaccaccaaacaggctttgtgtgagcaataaactgttttaatcacccg
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate