Basic Information
VIS ID
TVIS10016115
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
2505
Orient
+
Integrated sequence
GGGGTTCGCTGCCCCTTTTACACAATGTGGATTTCCTGCTTTAATGCCTTTATATGCATGTATTCAAGCTAAACAGGCTTTTACTTTCTCGCCAACTTAC| |AAGGCCTTTCTAAGCAAACAGTATCTGAACCTTTACCCCGTTGCTCGGCAACGGCCTGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGTTGGG
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
122585077/121572837 (Hg38)
End
122585077/121572837 (Hg38)
Orient
+
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/2247572; hsa-mir-10400/Downstream/1642951;
Nearest TSS
ENST00000518652/Upstream/659772; ENST00000522197/Downstream/66456;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/760357, chr8-CpG: 64/Downstream/66588
Nearby gene
SNTB1(-760768) ; HAS2(+40193) ;
Upstream sequence
aaaaaaattcagctgggcatgggagcgtgtgcctgtagttctagttactcaggagactgaggattgcttaagctcagaagtttgaggctagtgagctaag
Downstream sequence
tttcacctcctttccttattatgtaattttggggttttttcccctattgtgttacttctttctctcaggtatcatttccctagaatctttgctcctattt
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate