Basic Information
VIS ID
TVIS10016119
Fusion event
HBV-ATP5IF1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
345
End
386
Orient
+
Integrated sequence
TCAATGTTAATATGGGCCTAAAAATCAGACAACTATTGTGGT
Host Sequence
Chromosome
chr1
Cytoband
p35.3
Reference genome
GRCh37/hg19
Start
28564367/28237856 (Hg38)
End
28564410/28237899 (Hg38)
Orient
-
Location type
Intronic
Target gene
ATP5IF1
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-324-3p
Nearest miRNA
hsa-mir-12136/Upstream/1683263; hsa-mir-101-1/Downstream/2501257;
Nearest TSS
ENST00000473358/Upstream/1702; ENST00000605846/Downstream/3554;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1391, chr1-CpG: 27/Downstream/9291
Upstream sequence
GAATGAGCTGGGAATTCATGCTCTGAATCTATTTCCCCTGCTGCTTCTCCACTCCTCTATTCTCCCTCCCCTCTCCTCTTCGGCATTCACTGTAGCCTTG
Downstream sequence
TAAGAAGGAGATTGAGCGTCTGCAGAAAGAAATTGAGCGCCATAAGCAGAAGATCAAAATGCTAAAACATGATGATTAAGTGCACACCGTGTGCCATAGA
Target sequence
TGGCAGCTTTGAAAAAACACCATGAAGAAGAAATCGTTCATCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate