Fusion event
HBV-APOA2 integration
Disease
Hepatocellular carcinoma (HCC)
Integrated sequence
CCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAAAATCCTCACA
End
161193208/161223418 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/1323269; hsa-mir-1182/Downstream/3768;
Upstream sequence
gaaaccccgtctctactaaaaatacaaaaaattagctgggcgtggtggcaagtgcctataatcccaggtacttgggaggctgaggcaggagaattgcttg
Downstream sequence
GGGCGGCCTAGGAAGAGGGTGGTGGGGGTTTGGGGGACACTGAAGCCAAATGGGCTTCAGCTCCTCCCCAGGGATCTCCCTACCTGCTGCCCATTCCAAC
Target sequence
CCTTCAAGGCTGCAGATGGTGAGGAGTAGCACAGTTGCTGCGAGCAGCTTCATGTTGGTAACAGTGGGGA
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.