VISDB Viral Integration Site DataBase

VIS ID

TVIS10016121

Fusion event

HBV-PLEKHA6 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

1194

Orient

-

Integrated sequence

GATTCTTCCCCGATCATCAGTTGGACCCTGCATTCAAAGCCAACTCAGAAAATCCAGATTGGGACCTCAATCCATACAAGGACAACTGGCCGGATGCCAA| |CAAGGTGGGAGTGGGAGCATTCGGGCCAGGGTTCACCCCTCCCCATGGGGGCCTGTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTCACAACTGTGCCA

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

204235863/204266735 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-412-3p ; hsa-mir-136-5p ; hsa-mir-377-3p ; hsa-mir-485-5p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-3074-3p ; hsa-mir-410-3p ; hsa-mir-5011-5p ; hsa-mir-8066 ; hsa-mir-574-5p ; hsa-mir-1279 ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-2054 ; hsa-mir-6081 ; hsa-mir-3166 ; hsa-mir-4468 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-5699-5p ; hsa-mir-3121-3p ; hsa-mir-455-5p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-3605-5p ; hsa-mir-3679-5p ; hsa-mir-1185-5p ; hsa-mir-7162-3p ; hsa-mir-4649-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-3120-5p ; hsa-mir-6728-3p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-4714-5p ; hsa-mir-4290 ; hsa-mir-18a-3p ; hsa-mir-1324 ; hsa-mir-3163

Nearest miRNA

hsa-mir-101-1/Upstream/2263499; hsa-mir-1182/Downstream/1181567;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/8955, chr1-CpG: 62/Downstream/110869

Nearby gene

GOLT1A(-52643) ; LINC00628(+101694) ;

Upstream sequence

TGTCATTCTAGACATAaaaaggagaagaagaaagataaagacaaagaaagaagtagggatgaaagagaacgatcaacaagcaagaagaagaagagtaaag

Downstream sequence

ATACTTAAAATATCATCACAGCCAGTGAGCAGCTGTCAATGACCGGTCCCCTTACCTCAGCACTAGGTGGTGCTTGTATCTCCCTTCTGGCTGGCTGAGG