Basic Information
VIS ID
TVIS10016124
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1387
Orient
-
Integrated sequence
TGTGCCAGCAGCACCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGGCAGCCTACTCCCTTATCTCCACCTCTAAGGGACACTCATCCTCAGGCCATG| |CAGTGGAACTCCACCACTTTCCATCAAACTCTTCAAGATCCCAGAGTCAGGGCTCTGTATTTTCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAGCCCTG
Host Sequence
Chromosome
chr12
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
13667736/13514802 (Hg38)
End
13667736/13514802 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1244-3/Upstream/598884; hsa-let-7i/Downstream/4158497;
Nearest TSS
ENST00000382841/Upstream/127635; ENST00000621825/Downstream/25429;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/413105, chr12-CpG: 81/Downstream/48113
Nearby gene
LINC01559(-138057) ; GRIN2B(+46673) ;
Upstream sequence
cgcctcggaaaaaaaaaataaaaaatcccatgtaattagagtgatggcgtttccagtcccctcctacctctggggaaagaagaagatctgaagattgagt
Downstream sequence
AAGTATAgggtcacacactagatgcctgcaggggctgggcaggccacactgacaggaaggggaggcaggcaggggctgcaggggaccaggaagcctgtct
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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