Basic Information
VIS ID
TVIS10016126
Fusion event
HBV-PARP4P2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
2383
Orient
-
Integrated sequence
ATTGGGAGTTGGGGCTCCTTGCCACAGGAACATATTGTACAAAAAATCAAATTATGTTTTAGAAAACTTCCTGTCAACAGGCCTATTGATTGGAAAGTGT| |GTCAACGAATTGTAGGTCTTTTGGGGTTCGCTGCCCCTTTTACACAATGTGGATTTCCTGCTTTAATGCCTTTATATGCATGTATTCAAGCTAAACAGGC
Host Sequence
Chromosome
chr13
Cytoband
q12.11
Reference genome
GRCh37/hg19
Start
19969828/19395688 (Hg38)
End
19969828/19395688 (Hg38)
Orient
-
Location type
Intronic
Target gene
PARP4P2
Nearest miRNA
hsa-mir-1267/Downstream/1038090;
Nearest TSS
ENST00000623511/Upstream/50639; ENST00000438640/Downstream/13841;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/50607, chr13-CpG: 17/Downstream/164438
Nearby gene
LINC00421(-48939) ; TPTE2(+27190) ;
Upstream sequence
CGGGAGATTTATGAAATTTTGTCAAAGTGGTAGATCATGCTAAAGTCAGGGGAAATACTAGCACACTTTAGGTTGCTTCCTATTTTTAATTAAGTTTGAA
Downstream sequence
ACTGCATCTTTGCACTTGTGAGTGTGCATATAAATATATGTAAGTGCAGATGTGATGAACAATAATGCTGATCTATGCAGACATTCAAATTCACACACAA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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