Basic Information
VIS ID
TVIS10016128
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
406
Orient
+
Integrated sequence
TGGAAGATCCAGCATCCAGGGAATTAGTAGTCAGCTATGTCAATGTTAATATGGGCCTAAAAATCAGACAACTATTGTGGTTTCACATTTCCTGTCTTAC| |TTTTGGAAGAGAAACTGTTCTCGAATATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCTGCATATAGACCACCAAATGCCCCTATCTTATCAACA
Host Sequence
Chromosome
chr13
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
107511485/106859137 (Hg38)
End
107511485/106859137 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1297/Upstream/4813133; hsa-mir-1267/Downstream/672034;
Nearest TSS
ENST00000623511/Upstream/84858; ENST00000622038/Downstream/44962;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/290821, chr13-CpG: 48/Downstream/58690
Nearby gene
ARGLU1(-290971) ; FAM155A(+309393) ;
Upstream sequence
AGCAGATGTTAACTAGTATTGTTGAATATTTTCAACAAACATTTCGGGTGCTCAGGACACAGTCCTTTCTTATCTGTAGCTCTCTGTGTAACCTGTGCTG
Downstream sequence
TTTTCTCTCCTAACCATGCCCGAATGCATGAATTCAGTGGAGGTTATCGCATACCTACTGTGTCTCAGAGTCATTCCACAACCTCCCTAGGATGCCTTCA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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