BNC1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016131
Fusion event
HBV-BNC1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
2084
Orient
+
Integrated sequence
AACTGCACATGTATTCCCATCCCATCATCTTGGGCTTTCGCAAAATACCTATGGGAGTGGGCCTCAGTCCGTTTCTCATGGCTCAGTTTACTAGTGCCAT| |TTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTCTGGCTTTCAGTTATAGTGATGATATGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTT
Host Sequence
Chromosome
chr15
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
83924783/83256031 (Hg38)
End
83924783/83256031 (Hg38)
Orient
+
Location type
Intronic
Target gene
BNC1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10393/Upstream/188616; hsa-mir-11181/Downstream/2124565;
Nearest TSS
ENST00000557528/Upstream/48013; ENST00000492099/Downstream/27288;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/47704, chr15-CpG: 212/Downstream/27404
Nearby gene
HDGFL3(-48462) ; SH3GL3(+191307) ;
Upstream sequence
aTGAATATATACTTAGTATAAAAAGATACGTAGCAACAATTGGAGTCAATACACCAAATTTTAAGTGGTTGAGCTAAAATAGCAGGATAACAGTGACCTT
Downstream sequence
CAAGTTTTAAGTTGTCACACTTATTAAAACAAAAAAAGCTGAAATAATTGGTAACAGGTTGTTGGCTTTTTAACCTTTAGACCACAGAAATAATCTCTCT
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
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