Basic Information
VIS ID
TVIS10016132
Fusion event
HBV-chr15 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
472
Orient
+
Integrated sequence
GACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGAAGAGAAACTGTTCTCGAATATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCTGC| |ATATAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGC
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
92344374/91801144 (Hg38)
End
92344374/91801144 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-10393/Upstream/1794303; hsa-mir-1302-10/Downstream/1103255;
Nearest TSS
ENST00000557528/Upstream/152030; ENST00000555111/Downstream/52551;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/504034, chr15-CpG: 153/Downstream/51639
Nearby gene
SV2B(-499835) ; SLCO3A1(+52563) ;
Upstream sequence
ATATTGCAGCAGCTCCTGTCGGGTCTCTCCAAGTGAAAACACAGACGTCGCATGAAAATTCATCCTTCAAAGGCCTTGAGCAGCCAGGCCGTGCTGAGGG
Downstream sequence
TTATTAAGCAGCTCAACCTACCTGGCATTTATTGATAAATGTAGAATAATGTAGGGGTATATGGGAAACTACTTATGCTCAAATAATTTATTGATTAACA
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate