Basic Information
VIS ID
TVIS10016133
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
786
Orient
-
Integrated sequence
ACCTAACTTTAATCCTGATTGGCAAACTCCTTCTTTTCCTGACATTCATTTGCAGGAGGACATTGCTGATAGGTGTAAGCAATTTGTGGGACCCCTAACA| |GTAAATGAAAACAGGAGATTAAAATTAATTATGCCTGCTAGATTTTATCCCAATGTTACCAAATACTTGCCCTTAGATAAAGGAATTAAACCCTATTATC
Host Sequence
Chromosome
chr16
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
46427790/46393878 (Hg38)
End
46427790/46393878 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1225/Upstream/12230205; hsa-mir-11401/Downstream/3898738;
Nearest TSS
ENST00000527434/Upstream/10606991; ENST00000569239/Downstream/190375;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/10291165, chr16-CpG: 124/Downstream/33580
Nearby gene
LINC02167(-11436795) ; ANKRD26P1(+75458) ;
Upstream sequence
ggctaacacctgcaatcccagcactttgggaggccaaggcaggtggatcacaaggtcaggagtccgagaaggtgaaaccccgtctctattaaaaatacaa
Downstream sequence
caatagaatcatcatggaattgaatcgaattgctcaccgtcgaatggaatcaaatggaatcaccgaatggaatcgaatggaatcatcattgaatggaatc
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate