Basic Information
VIS ID
TVIS10016134
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
890
Orient
-
Integrated sequence
ATGAAAACAGGAGATTAAAATTAATTATGCCTGCTAGATTTTATCCCAATGTTACCAAATACTTGCCCTTAGATAAAGGAATTAAACCCTATTATCCAGA| |GCATGTAGTTAATCATTACTTCCAGACGAGACATTATTTACATACTCTTTGGAAGGCGGGTATCTTATATAAAAGAGAGACGACACGTAGCGCCTCATTT
Host Sequence
Chromosome
chr16
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
46428634/46394722 (Hg38)
End
46428634/46394722 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1225/Upstream/12231049; hsa-mir-11401/Downstream/3897894;
Nearest TSS
ENST00000527434/Upstream/10607835; ENST00000569239/Downstream/189531;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/10292009, chr16-CpG: 124/Downstream/32736
Nearby gene
LINC02167(-11437639) ; ANKRD26P1(+74614) ;
Upstream sequence
ggaatcatcatcgaattgactcatatggaatcatcgtcgaatggattccaatggaatcatcatcgaatggatttgaatggaaacatcatctaactgaatc
Downstream sequence
caccgtcgaatggaatcaaatggaatcatcgaatggaatcgaatggaatcatcatcgaatggaatgaaatggaatcatccaatggacgagaagtgaatca
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate