VISDB Viral Integration Site DataBase

VIS ID

TVIS10016135

Fusion event

HBV-LONP2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Start

494

Orient

-

Integrated sequence

TTCCTGTCTTACTTTTGGAAGAGAAACTGTTCTCGAATATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCTGCATATAGACCACCAAATGCCCCT| |ATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCACCGC

Chromosome

chr16

Cytoband

q12.1

Reference genome

Start

End

48311098/48277187 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-505-5p ; hsa-mir-30c-2-3p ; hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-3692-5p ; hsa-mir-22-3p ; hsa-mir-1182 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-1915-3p ; hsa-mir-3664-5p ; hsa-mir-3672 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4639-3p ; hsa-mir-6764-5p ; hsa-mir-6794-3p ; hsa-mir-6864-3p ; hsa-mir-8055

Nearest miRNA

hsa-mir-1225/Upstream/14113514; hsa-mir-11401/Downstream/2015429;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/32443, chr16-CpG: 30/Downstream/88632

Nearby gene

ABCC11(-42010) ; SIAH1(+83347) ;

Upstream sequence

cgccgaatggattccaatggaataatcatggaatggattcgaatggaaacatcatctaattgaatcaaatagaatcatcatggaattgaatcgaattgct

Downstream sequence

TCATAGTGCCTTTTAAATACATAGTACCTCTTTGCTATATTATAGTGATAGCTAAATGATCTTTTCACATTCCTAAGTTTTGATTTCTGAATGGCGTCGC