Basic Information
VIS ID
TVIS10016136
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22267523
Virus Sequence
Virus name
HBV
Reference genome
AY033073.1
Start
1148
Orient
+
Integrated sequence
CCTCGAAAAGGCATGGGGACAAATCTTTCTGTCCCCAATCCACTGGGATTCTTCCCCGATCATCAGTTGGACCCTGCATTCAAAGCCAACTCAGAAAATC| |CAGATTGGGACCTCAATCCATACAAGGACAACTGGCCGGATGCCAACAAGGTGGGAGTGGGAGCATTCGGGCCAGGGTTCACCCCTCCCCATGGGGGCCT
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
GRCh37/hg19
Start
57326953/57293041 (Hg38)
End
57326953/57293041 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/388688; hsa-mir-11401/Downstream/479248;
Nearest TSS
ENST00000527434/Upstream/8354; ENST00000219235/Downstream/65731;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/7989, chr16-CpG: 26/Downstream/89021
Nearby gene
PLLP(-8369) ; CCL22(+65741) ;
Upstream sequence
ATGGCAAAATGTGATACAGTTCTTCCAATATCATGGGCAACTTGTAGCCAGAATTAAGTAGAAGATAAGATTAGAATTGAATATAATAACTTTTGATTTA
Downstream sequence
gtcacacattgatgctgggaaagtaacgctgtccctgattccacagggagaggataatggaggttccaggtttggaactttcctagccccttccctatac
Reference
Jiang, S., et al. Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PLoS One ,2012, 7(9): e40363.
Curate